Global Natural Killer Cells Market Is Expanding Owing To Growing Incidences Of Chronic Diseases

 

Natural Killer Cells Market

Natural killer cells are fighters in the innate immune system. A type of immune cell that possesses granules containing enzymes that can kill cancer cells and other malignant cells. A subset of these cells are called memory NK cells. Unlike T cells, which are part of the adaptive immune system and must "remember" previous infections in order to respond, memory NK cells can be activated at a moment's notice without prior sensitization. The mechanisms by which NK cells differentiate between ‘self' and 'non-self' cells to initiate killing is complex, but recognition of an altered self-state by NK receptors expressing polymorphic inhibitory ligands (such as CD16) is thought to play an important role. NK cells are unique among the frontline immune cells as they can attack viruses and tumors in their early stages without first being primed by antigen-presenting cells. They also secrete cytokines that recruit other immune system cells to assist in the fight.

Market Dynamics:

Rising acquisitions among key players are estimated to augment growth of the global Natural Killer Cells Market during the forecast period. For instance, Adaptate biotherapeutics was acquired by Takeda, in January 2022. This acquisition will help in the development of novel gamma delta (γδ) T cell engager therapies for targeting solid tumors. Moreover, lack of specificity is anticipated to restrain growth of the global natural killer cells market during the forecast period.

Impact of COVID-19:

The pandemic was first reported in 2019 in China and later on it was transmitted to other nations globally. The pandemic resulted in imposition of strict nationwide lockdowns in many regions. Several countries had to ban travel for preventing further spread of the virus. The pandemic had a significant impact on the healthcare sector. The number of patients suffering from COVID-19 was increasing on a daily basis. This caused hospitals and healthcare professionals to prioritize COVID-19 patients. All resources were being used to treat these patients. This hampered the growth of the global Natural Killer Cells Market. However, the market is estimated to witness growth in the post-pandemic era, as all restrictions have been eased.

Key Takeaways:

The global Natural Killer Cells Market is expected to witness high growth, exhibiting CAGR of 43.1 % over the forecast period, due to increasing clinical trials. For instance, Nektar Therapeutics declared initiating phase 1b data in patients suffering from atopic dermatitis for novel T regulatory cell stimulator NKTR-358, in December 2021. NKTR-358 has been designed for treating inflammatory and autoimmune conditions.

North America is anticipated to witness significant growth in the global Natural Killer Cells Market during the forecast period, due to growing technological advancements and increasing presence of key players.

Key players operating in the global natural killer cells market are Regeneron Pharmaceuticals Inc., Merck KGaA, Takeda Pharmaceutical Company Limited, Bristol-Myers Squibb Company, iCell Gene Therapeutics, Glycostem, Multimmune GmbH, Sanofi, Affimed GmbH, Cytovia Therapeutics, Acepodia Inc., ImmunityBio, Inc., Gamida Cell, Biohaven Pharmaceuticals, Innate Pharma, Inc., Fate Therapeutics, PersonGen BioTherapeutics, EMERcell, and Phio Pharmaceuticals.

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